Diagnostic reliability of Widal slide agglutination test for enteric fever- still a query

Comparison of the diagnostic value of local Widal slide test with imported Widal slide test.

A laboratory study comparing the Widal slide agglutination test using local antigens produced by Mekar Jaya Diagnostica (SAT-MJD) with imported antigens (Murex, Abbott) was carried out on 55 sera of typhoid fever patients with positive blood culture and 56 sera of non-typhoid febrile patients. The SAT-MJD antigens consisted of a mixture of 5 different phage-types of S. typhi dominantly found in...

Widal agglutination test - 100 years later: still plagued by controversy.

We review the significance of the Widal agglutination test in the diagnosis of typhoid fever. Over 100 years since its introduction as a serologic means of detecting the presence of typhoid fever, the Widal test continues to be plagued with controversies involving the quality of the antigens used and interpretation of the result, particularly in endemic areas. Areas of concern with clinical and...

Significance of Modified Widal Test with Conventional Widal Test in the Diagnosis of Enteric Fever

Enteric fever is a systemic infection caused by Salmonella serotypes; S. typhi, S. paratyphi A, S. paratyphi B, S. paratyphi Cand S. sendai (Mandell GL et al, Parker MT). It is characterized by malaise, fever, abdominal discomfort, transient rash, splenomegaly, hepatomegaly, bradycardia, and leucopenia. Major complications are intestinal hemorrhage and perforation (Hook EW et al). It is still a...

The Vi-Agglutination Test in Enteric Fever

Comparison of passive haemagglutination test with Widal agglutination test for serological diagnosis of typhoid fever in an endemic area.

A passive haemagglutination test, using sheep red blood cells sensitised with Salmonella typhi lipopolysaccharide, was compared with the Widal test for the serological diagnosis of typhoid fever in an endemic area. The results obtained on sera from 152 patients with bacteriologically confirmed typhoid and 183 patients who did not have typhoid were analysed in terms of sensitivity, specificity, ...